Matific has also announced the launch of its award winning solution ‘Matific Galaxy (MG)’ with a motive of addressing the gap noticed in teaching Maths. The solution MG is said to having been launched at an affordable price.

Matific Galaxy features maths activities aligned with school curriculums of ICSE, CBSE boards. Matific’s home product aims to provide a solution to conventional home-schooling and ensure that kids are well prepared for the future and up to pace until the lock down period ends.

The evidence-based content has been proven to help improve students’ math results by 34%. The program provides parents with access to a dashboard where they can keep track of their child’s mathematics achievements and progress.

Schools as of now are going online to teach their students owing to COVID-19, given the present situation perhaps returning to schools may not be possible soon.

Also read ‘IIIT Delhi comes up with innovative solution to battle COVID-19‘

And, the solutions enable students to continue their learning process. MG is an award-winning unique platform offering online gamified Maths resources and engaging activities that promote conceptual understanding and problem-solving skills for kids from Nursery to Sixth standard.

Vibha Mahajan, VP, Matific India said MG is backed by extensive research and designed by senior mathematics professors and curriculum experts, making it the most comprehensive online mathematics resource.

‘We want to ensure that all students in all areas of India have the opportunity to continue learning during this time. This means ensuring that the price is not an issue.’

MG is offering an annual plan for just INR 210 per month, which is a practical choice considering its high-quality content and costly solutions in the education space.

Matific also offers a 7-day free trial for students. Apart from offering the most advanced and relevant content at the most affordable price, MG works in offline mode as well, taking out the significant overheads of data consumption.

Matific has several games and stimulating maths activities, each of which is equally gripping so that kids end up playing for hours, and learning maths in a process of self-guided discovery.

Playful interactions, colourful characters, and gamification help ease math anxiety and boost math confidence amongst students.

Matific is present in over 45 countries with adaptability in 26 languages across the world and has proven to help improve student’s math test scores by 34%.

Used by thousands of teachers worldwide, it provides relief to parents and enjoyable experience to children during a time of uncertainty. Every day over thousands of teachers and students log in for online teaching and learning.

Available both on ‘Google Play’ and ‘App Store’ MG program can be accessed on desktop, tablets and mobile devices.

About Matific

Matific is part of a global educational technology company whose founders include top Australian businessman Leon Kamenev, who has launched several high-profile online companies including Menulog and HotelClub. Matific aims to make maths fun and engaging for all students.

The MG App was launched in May 2018 to introduce a new, fun, and simple way of approaching maths that simultaneously helps young students develop a lifelong appreciation for the subject and its applications.

The Matific resource, which is currently in 45 countries and translated into 26 languages, has been getting excellent results worldwide.

This innovative hydrogel-based therapy delivers anti-cancer drugs directly to tumor sites, significantly reducing the side effects typically associated with conventional cancer treatments.

The paper is co-authored by Prof. Debapratim Das, along with his research scholars Ms. Tanushree Das and Ms. Ritvika Kushwaha from IIT Guwahati, and collaborators Dr. Kuldip Jana, Mr. Satyajit Halder, and Mr. Anup Kumar Misra from Bose Institute Kolkata.

Surgical removal of tumors is sometimes not feasible, particularly for internal organs, while chemotherapy’s systemic delivery often results in harmful side effects by affecting both cancerous and healthy cells.

Design

Prof. Debpratim Das, Department of Chemistry, and his team at IIT Guwahati addressed these challenges by designing a hydrogel that delivers drugs precisely to the tumor site, ensuring localized action.

Water-based

Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids. Their unique structure mimics living tissues, making them suitable for biomedical applications.

This newly developed hydrogel acts as a stable reservoir for anti-cancer drugs and releases them in a controlled manner, responding to specific conditions in the tumor microenvironment, say researchers from IIT Guwahati.

It responds to elevated glutathione (GSH) levels, a molecule abundant in tumor cells.

Upon encountering high GSH levels, the hydrogel triggers a controlled drug release directly into the tumor, minimizing its interaction with healthy tissues and reducing systemic side effects, say sources from IIT Guwahati.

Department of Chemistry at IIT Guwahati

Speaking about the breakthrough, Prof. Debapratim Das, Dept. of Chemistry, IIT Guwahati, said, “This work exemplifies how scientific innovation can directly address the pressing needs of cancer treatment.

The hydrogel’s unique properties allow it to work in harmony with the biological environment, offering precision where it is needed most, said Prof Debapratim Das of IIT Guwahati.

We are excited by its potential to transform our thoughts about localized drug delivery, he said.

Preclinical trials

In preclinical trials on a murine model of breast cancer, the hydrogel showcased remarkable efficacy.

A single injection of the hydrogel, loaded with the chemotherapy drug Doxorubicin, resulted in a ~75% reduction in tumor size within 18 days.

Crucially, the hydrogel remained localized at the tumor site, steadily releasing the drug over time without causing detectable side effects on other organs.

Delivery system

This innovative delivery system enhances the drug’s effectiveness while reducing the required dosage, thus minimizing toxicity.

Laboratory studies further demonstrated that the hydrogel improves drug uptake by cancer cells, induces cell cycle arrest, and promotes programmed cell death, thereby attacking tumors on multiple fronts.

Further studies

Further studies are going on to find out the maximum amount of reduction in the size of the tumor by a single dose. Moreover, we are also looking into other types of tumors, say sources from IIT Guwahati.

Once all the studies are complete, will apply to take the material for clinical trial and are looking for an appropriate partner to do the same.

At present, the Institute has eleven departments, nine interdisciplinary academic centres and five schools.

They are covering all the major engineering, science, healthcare, management, and humanities disciplines, offering BTech, BDes, BSc(Hons), MA, MDes, MTech, MSc, MS(R), MBA and PhD programmes.

The institute offers a residential campus to 455 faculty members and more than 8,600 students at present.

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