IIT Kanpur researchers achieve landmark visualization

IIT Kanpur researchers achieve landmark visualization
Published at : 6 Aug 2024, 6:23 PM IST
Updated at : 6 Aug 2024, 6:24 PM IST

IIT Kanpur research team led by Prof. Arun K. Shukla has made a significant scientific breakthrough.

They have made a breakthrough with the first-ever visualization of the complete structure of the Duffy antigen receptor.

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IIT Kanpur

It facilitates infections by destructive pathogens like the malaria parasite, Plasmodium vivax and the bacterium, Staphylococcus aureus, say sources from IIT Kanpur.

Prof Arun is from the Department of Biological Sciences and Bioengineering, say sources from IIT Kanpur.

Research Paper

The research paper on the discovery, published in Cell, a peer-reviewed prestigious scientific journal, will arm scientists working in the field of antimicrobial drug resistance with new information to further their research, say sources from IIT Kanpur.

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Given the rising challenges of drug-resistant infections, the visualisation of the structure of the Duffy receptor will pave the way for further research.

It will pave way for research into novel therapies for drug-resistant malaria and Staphylococcus infections as well as infections like HIV, say IIT Kanpur researchers.

Unravel

Prof Arun K Shukla from Department of Biological Sciences and Bioengineering at IIT Kanpur spoke about the research work.

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For years, researchers around the world have been trying to unravel the secrets of the Duffy antigen receptor, given its role in acting as a ‘gateway’ to help bacteria and parasites attack our cells and cause disease, said Prof Arun of IIT Kanpur.

Our success in finally visualizing this receptor at a high resolution will help us understand how pathogens exploit it to infect the cells, he said.

The knowledge will support the designing of next-generation medicines including new antibiotics and antimalarials, especially at a time when we are facing escalating antimicrobial resistance, he said.

Common

While the Duffy antigen receptor is common in most populations, a significant percentage of people of African descent do not produce the Duffy receptor on their red blood cells due to a genetic variation, said Prof Arun from IIT Kanpur.

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This makes them naturally resistant to certain types of malaria parasites that rely on that specific ‘gateway’ to infect those cells, says Prof Arun.

This shows how important the Duffy antigen receptor is for these diseases and how targeting it could lead to new treatments, added Prof. Shukla.

IIT Kanpur

This threw new light on the Duffy receptor’s unique structural features and distinguishing it from similar receptors in the human body.

This detailed understanding will be crucial in the designing of highly targeted therapies that can effectively block infections without causing unwanted side effects.

Director of IIT Kanpur

Prof. Manindra Agrawal, Director, IIT Kanpur spoke about the research. This remarkable achievement by our team of researchers is one more laurel in IIT Kanpur’s crown of achievements, pushing the boundaries of scientific knowledge.

The success of this research will enhance our understanding of infectious diseases and help develop therapies for drug-resistant pathogens, said director of IIT Kanpur.

This is a result of IIT Kanpur’s support to cutting-edge research that addresses real-world problems and solidifies our standing on the global scientific stage, he said.

IIT Kanpur

It also comprised Manisankar Ganguly, Divyanshu Tiwari, Ramanuj Banerjee along with and Prof. Arun Kumar Shukla from IIT Kanpur.

In addition, the team also included researchers from CDRI Lucknow, Zurich in Switzerland, Suwon in Republic of Korea, Tohoku in Japan, and Belfast in United Kingdom.

This research was funded primarily by the Department of Biotechnology (DBT), Department of Science and Technology (DST), Science and Engineering Research Board (SERB), DBT Wellcome Trust India Alliance, and IIT Kanpur.

S.
S. Vishnu Sharma

S Vishnu Sharmaa now works with collegechalo.com in the news team. His work involves writing articles related to the education sector in India with a keen focus on higher education issues. Journalism has always been a passion for him. He has more than 10 years of enriching experience with various media organizations like Eenadu, Webdunia, News Today, Infodea. He also has a strong interest in writing about defence and railway related issues.

WBJEE 2025 registration Starts 22 January 2025, All Information Here

WBJEE 2025 registration Starts 22 January 2025, All Information Here
Published at : 23 Jan 2025, 4:17 PM IST
Updated at : 23 Jan 2025, 4:17 PM IST

WBJEE 2025 registration has started at ‘https://wbjeeb.nic.in/wbjee/’ from 22 January 2025. The last date to apply for the exam is 23 February 2025.

Students who are keen on seeking admission in engineering, pharmacy and architecture in graduation in colleges in West Bengal can apply for this exam conducted by West Bengal Joint Entrance Examinations Board (WBJEEB).

Admission Open in Amity for 2025
WBJEE 2025 registration

The download of admit card can be done from 17 to 27 April 2025. Exam will be conducted on 27 April 2025. Paper 1 (mathematics) will be conducted from 11 AM to 1 PM.

Paper 2 (physics and chemistry) will take place from 2 PM to 4 PM. The date for announcement of results will be informed later.

Admission Open in SRM for 2025

Eligibility for WBJEE 2025 registration

Candidates who have passed plus-two from a recognized institution with subjects as maths/biology, physics and chemistry can take up WBJEE 2025 registration.

Students who are trying to apply for pharmacy course at undergraduate level have to pass plus-two with biology, physics and chemistry as subjects.

Point to remember

Even students who are studying in plus-two and are about to appear for the plus-two exams also take up WBJEE 2025 registration (submitting application for the exam).

Admission Open in LPU for 2025

However, they should have passed the exam and should be able to produce the required certificate in support at the time of admission commencement for undergraduate courses.

Age limit and nativity

The lower age limit for taking up WBJEE 2025 registration is 17. There is no upper age limit for appearing for the exam.

The upper age limit to apply for Marine Engineering course is 25 years. Those wishing to take up WBJEE 2025 registration have to preferably be natives of West Bengal.

Admission Open in VIT for 2025
WBJEE 2025 registration

Registration fee

WBJEE 2025 registration fee is Rs 500, Rs 400 Rs 300 for male, female and third gender applicants of general category.

The same is Rs 400, Rs 300 and Rs 200 for male, female and third gender applicants from SC/ST/OBC-A/OBC-B/EWS/PwD/TFW categories.

How to take up WBJEE 2025 registration?

The process to take up WBJEE 2025 registration is online and applications can be submitted at the official website ‘https://wbjeeb.nic.in/wbjee/’

  1. The URL mentioned above has to be typed into the browser and submitted to allow the website to download.
  2. Once the website is ready, candidates can scroll down the webpage and click Online Application Form Submission for WBJEE 2025 under CANDIDATE ACTIVITY BOARD column
  3. Clicking the above button will open another webpage with URL ‘https://admissions.nic.in/WBJEEB/Applicant/Root/Home.aspx?enc=yVQCIiq12npg+pcvNJRdc+MheI+oZUchuf9ZqngYKB9TC2Er0Y8MST/kUytnWCwR’
  4. Once the website with URL opens, candidates can click New Candidate Registration button to create an account with username and password.
  5. After creating the account, candidates can come back to the webpage with URL ‘https://admissions.nic.in/WBJEEB/Applicant/Root/Home.aspx?enc=yVQCIiq12npg+pcvNJRdc+MheI+oZUchuf9ZqngYKB9TC2Er0Y8MST/kUytnWCwR’ and login and start taking up WBJEE 2024 registration.

Direct link to take up WBJEE 2025 registration is here

Documents

Candidates have to upload the documents mentioned below during WBJEE 2025 registration:

# Candidate’s photograph

# Scanned image of candidate’s signature

# 10th class marksheet

# 12th class marksheet (if available) or its alternative as suggested

# Category certificate (if applicable) for those who wish to claim facilities like reservation

Exam pattern

The exam will have questions in multiple choice format which are related to maths/biology, physics and chemistry taught in plus-two classes in recognized institutions.

The total number of marks for this exam are 200. There will be 75 questions related to maths, 40 questions each related to physics and chemistry.

Students have to mark their answers on a separate OMR sheets for each question by darkening the respective circle. Every correct reply will fetch 1 mark and wrong answer would give 25% negative marks.

For questions that have more than one correct replies, candidates have to mark all the correct replies to get full marks.

Admit card

Candidates who have successfully completed their WBJEE 2025 registration can alone download the admit card for the exam. The link for downloading it will be made active at the appropriate time.

Candidates can visit the official website to download the admit card. Hall tickets may not be sent to the candidates by post. Process to obtain hall ticket is mentioned below:

1. The official website of the exam must be accessed with the help of URL ‘https://wbjeeb.nic.in/wbjee/’

2. Once the website is ready, candidates can click the link for downloading the hall ticket.

3. After clicking the link, they must enter their application number, date of birth and other details and submit them to download the admit card.

WBJEE 2025 registration

After the exam

Candidates must pass the exam with the required qualifying marks to be eligible for the next phase of the admission process which involves counselling.

Schedule for the counselling will be informed in the due course, mostly after the release of results for WBJEE 2025 exam.

Those who have passed the written test with the required qualifying marks can alone register for the counselling.

The process of counselling comprises choosing colleges for studying the course. Those who get a seat can pay the fee and join the classes at the institute allotted.

S.
S. Vishnu Sharma

S Vishnu Sharmaa now works with collegechalo.com in the news team. His work involves writing articles related to the education sector in India with a keen focus on higher education issues. Journalism has always been a passion for him. He has more than 10 years of enriching experience with various media organizations like Eenadu, Webdunia, News Today, Infodea. He also has a strong interest in writing about defence and railway related issues.



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