The team of researchers were from IIT Bhilai, Shiv Nadar Institution of Eminence, Delhi, NCR, and Shri Rawatpura Sarkar Institute of Pharmacy of Chhattisgarh.

The study led by Dr Suchetan Pal, Assistant Professor, Department of Chemistry, IIT Bhilai, promises a safe and efficient method of supplying Insulin to insulin-dependent diabetic patients.

They do not work quite like the body’s natural system and can be fatal. The current Insulin injection methods can also make blood sugar levels drop dangerously low, and patients might have to rely on them forever, says Dr Suchetan from IIT Bhilai.

Improved methods

Seeking improved methods of insulin delivery, the researchers at IIT Bhilai explored the innovative application of hydrogels. Hydrogels are biocompatible polymers that are characterized by high water content and are being studied for controlled drug release in various medical fields including cardiology, oncology, immunology, wound healing, and pain management.

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The researchers encapsulated insulin in specially designed hydrogels that can be administered instead of direct insulin injections, say sources from IIT Bhilai.

This was achieved by crosslinking polyvinyl alcohol with tiny particles of chitosan, an ingredient derived from shellfish and crabs’ outer skeletons, say sources from IIT Bhilai.

The crosslinker, formylphenylboronic acid (FPBA), responds to glucose levels and releases the insulin that is encapsulated inside the hydrogel.

Through comprehensive experiments involving small-molecule drug analogs and macromolecular insulin, the team demonstrated that the hydrogels released insulin predominantly under hyperglycemic (high glucose) conditions, say sources from IIT Bhilai.

The safety and antidiabetic efficacy of insulin-loaded hydrogels were confirmed through tests in a type I rat model.

Versatility

Emphasizing the versatility of these hydrogels, Dr. Pal added, “These modular hydrogels can take the form of microneedles or oral formulations and can prove sustained delivery of insulin in response to elevated blood glucose levels.

This could significantly enhance convenience and safety for patients requiring insulin therapy, said Dr Pal of IIT Bhilai.

Paper

In a paper co-authored by Mr. Akbar Ali, Ms. Saroj, Ms. Sunita Saha, Mr. Sanjay Kumar Gupta, Dr Tatini Rakshit, and Dr Suchetan Pal, the findings of this ground-breaking research have been published in the American Chemical Society journal, Applied Materials and Interfaces.

This chronic health ailment, stemming from inadequate insulin generation in the pancreas, results in high blood sugar levels and presents considerable health risks, say sources from IIT Bhilai.

Insulin remains a cornerstone therapy for many patients with type 1 diabetes. Presently, individuals with diabetes often resort to daily insulin injections using needles or specialized devices to manage their blood sugar levels.

It is estimated that around three million people in India rely on insulin therapy, say sources from IIT Bhilai.

About IIT Bhilai

Indian Institute of Technology Bhilai was established in the State of Chhattisgarh by Ministry of Human Resource and Development in the year 2016.

IIT Bhilai offers Bachelor of Technology (BTech), Master of Technology (MTech), Master of Science (MSc) and Doctoral programs (PhD) in various departments.

IIT Bhilai has established a 3-D Printing Lab that constitutes an integral part of 3-D Modeling and Design course, a fabrication lab, an electrical lab, a computer lab and a library in a short duration.

The date for the exam has been announced in a notification by NBEMS (National Board of Examinations in Medical Sciences).

Schedule

This is all about the commencement of application submission for NEET MDS 2025 Exam.

As per estimates, the registration for NEET MDS 2025 Exam will likely commence in December 2024.

It is usual to open the application submission for an exam about a month or two before the date on which the exam would be conducted.

Taking that into account, the registration for NEET MDS 2025 exam is expected to start by December 2024 or by January 2025.

This is however a guess work, the exact dates will only be known when the official notification for NEET MDS 2025 exam will be out.

What is NEET MDS?

NEET MDS is expanded into National Eligibility Cum Entrance Test for Master in Dental Surgery (NEET MDS).

It is conducted once every year for providing admission into postgraduate dental courses in colleges located across India.

NEET MDS 2025 exam is meant to be held in 2025 and is conducted by National Board of Examinations in Medical Sciences (NBEMS). NEET MDS 2025 exam registration nothing but applying for the exam.

Who can apply for NEET MDS 2025 Exam?

Candidates who have passed graduation in dental sciences (BDS) from a recognized educational institution anywhere in India can apply for NEET MDS 2025 exam.

Applicants must also have completed the required internship (CRI or CRRI) and have the required registration with DCI (Dental Council of India) or State Dental Councils.

1. The URL mentioned above must be typed into the browser and submitted to allow the website to download.

2. Once the website is ready, candidates can click the button NEET MDS under Entrance Examinations menu.

3. Clicking the above button will open another webpage with URL ‘https://natboard.edu.in/viewnbeexam?exam=neetmds’

4. Once the webpage with above URL opens, candidates can click the button Application Link.

5. Clicking the above button will open another webpage with URL ‘https://cdn3.digialm.com/EForms/configuredHtml/1815/81662/Index.html’

6. After the webpage with above URL is open, candidates can register and create an account with username and password.

7. After creating an account, candidates can login and fill the NEET MDS 2025 Exam application.

Website For NEET MDS 2025 Exam is Here

Registration fee

Candidates submitting NEET MDS 2025 exam application have to pay Rs 3500 if they are from General, OBC and EWS categories. The same for those from SC/ST/PwD categories is Rs 2500.

The amount mentioned above can change due to various reasons, candidates can refer the information brochure on the official website mentioned above at the time of registration for latest information.

The link for it will be activated at the appropriate time on the official website. The link will turn active about 10 or 20 days before the exam day. It can be downloaded as per the instructions below:

1. Type the URL ‘https://natboard.edu.in/viewnbeexam?exam=neetmds’ in the browser and submit it for allowing it to download.

2. Once the website is ready, the link for admit card has to be clicked.

3. After clicking the link, candidates have to enter their application number, date of birth and other details and submit them to obtain the hall ticket.

Candidates can appear for the exam with their hall tickets.

They have to pass the exam with required qualifying marks to be eligible for the next phase of admission which comprises counselling.

Counselling is the phase where candidates can choose the course and the college they wish to study it.

Those who do not get a seat in college of their choice in the initial rounds, can try in the subsequent rounds. Individuals who get a seat can pay the fees and join the institution for classes.

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